Hotel guide
A hotel in Key West should make the parts of the trip you care about easier. Use the location, pace, and booking notes below to narrow the field before you compare rooms.
Choose a property here once you know the kind of stay you want. Not sure which part of town to book? Use the Key West stay matcher before comparing rooms.
The Marquesa Hotel is a standout fit for couples and small groups who want the city's core at their doorstep.
Best for: Boutique, Old Town, Walkable
Before you go: Reserve before you build the rest of the day around it.
A comfortable base when you want more fitting value without losing too much location quality.
Best for: Balanced, Pool, Convenient
Before you go: Reserve before you build the rest of the day around it.
Pier House Resort & Spa is a Key West splurge with waterfront advantages and easy reach to Old Town energy.
Best for: Waterfront, Resort, Old Town
Before you go: Reserve before you build the rest of the day around it.
Best when the goal is being in Key West at all, not maximizing hotel glamour.
Best for: Value, Simple, Island base
Before you go: Reserve before you build the rest of the day around it.
A larger South End resort base when beach access and a spread-out property matter more than being mid-Duval.
Best for: Beach access, Resort, Southernmost
Before you go: Reserve before you build the rest of the day around it.
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Rates, availability, amenities, and parking rules change often. Confirm the details directly with the property before booking. Last destination review: 2026-06-19.